Introduction: Can automated breast density measures be used in place of radiologist-assessed breast density?
Methods: Automated and radiologist-assessed breast density was measured on digital mammography in 1609 women with screen-detected cancer, 351 women with interval invasive cancer, and 4409 matched control participants.
Results: Mammography sensitivity was similar for automated and radioloist-assessed BI-RADS categories: fatty, 93% versus 92%; scattered fibroglandular densities, 90% versus 90%; heterogeneously dense, 82% versus 78%; and extremely dense, 63% versus 64%, respectively
Conclusion: Automated and radiologist-assessed BI-RADS density similarly predicts interval and screen-detected cancer risk, suggesting that either measure may be used to inform women of their breast density.
Authors: Kerlikowske K, Scott CG, Mahmoudzadeh AP, Ma L, Winham S, Jensen MR, Wu FF, Malkov S, Pankratz VS, Cummings SR, Shepherd JA, Brandt KR, Miglioretti DL, Vachon CM.
Annals of Internal Medicine 2018
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